The Manifesto, establishing Institute Para Limes, was signed on 30 August, 2005 in Ruurlo, The Netherlands.

Founding Fathers of Institute Para Limes:

Professor Bertil Andersson (CEO European Science Foundation)
Professor W. Brian Arthur (Santa Fe Institute, New Mexico)
Professor Maarten Boasson (University of Amsterdam)
Professor Rob de Boer (University of Utrecht)
Professor Sydney Brenner (University of Cambridge, Nobel laureate)
Professor Manuel Castells (Universitat Oberta de Catalunya)
Professor Jean Pierre Changeux (Institute Pasteur, Paris)
Professor Esteban Domingo (University of Madrid)
Professor Manfred Eigen (Max Planck Institut, Göttingen. Nobel Laureate)
Professor Alan Fersht (University of Cambridge)
Professor Daan Frenkel (FOM Institute for Atomic and Molecular Physics)
Professor Tim Hunt (London Research Institute, Clare Hall Laboratories, Nobel Laureate)
Professor John Holland (University of Michigan at Ann Arbor)
Professor Paul Hooykaas (University of Leiden)
Professor Robert Huber (Max Planck Institut, Martinsried, Nobel Laureate)
Professor Jean Marie Lehn (College de France, Strasbourg, Nobel Laureate)
Professor Robert May (University of Oxford)
Professor Erling Norrby (Royal Swedish Academy of Sciences)
Professor Peter Nijkamp (Free University Amsterdam)
Professor Martin Rees (University of Cambridge)
Professor Marten Scheffer (Wageningen University)
Professor Peter Schuster (Institut für Theoretische Chemie, Vienna)
Professor Ismail Serageldin (Library of Alexandria)
Professor Jan de Vries (UC at Berkeley)

On behalf of the Foundation responsible for the initiative to develop the Para Limes Institute were:

Professor Rudy Rabbinge (Wageningen University, Chairman)
Dr Theo Groen
Professor Jan Stuip
Mr Jan Wouter Vasbinder